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Diabetes Care, Vol 11, Issue 10 801-807, Copyright © 1988 by American Diabetes Association

ARTICLES

Laboratory evaluation of new reusable blood glucose sensor

SJ Updike, MC Shults, CC Capelli, D von Heimburg, RK Rhodes, N Joseph-Tipton, B Anderson and DD Koch
Department of Medicine, University of Wisconsin Center for Health Sciences, Madison.

An enzyme-electrode sensor designed specifically for pocket-portable self-monitoring of blood glucose is described. The sensing device in this instrument is unique because it is reusable for at least 30 days, at which time it is easily replaced by placing a new enzyme-membrane cartridge over the electrode. As little as 7 microliters of undiluted whole blood, plasma, or serum is applied directly to the sensor, and glucose is automatically determined in 30 s. No manual timing or wiping step is required after sample application. On eight production instruments, plasma glucose concentration was determined (n = 20) at 57, 125, 246, and 347 mg/dl. The average coefficient of variation for the 80 determinations for each instrument ranged from 2 to 5%, averaging 3.7%. The instrument is inherently linear, independent of hematocrit, and without oxygen limitation when dissolved oxygen concentration is greater than 35 mmHg. No interferences were found from plasma constituents, heparin, or acetaminophen.
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Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1988 by the American Diabetes Association.