Diabetes Care
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Diabetes Care, Vol 13, Issue 3 188-197, Copyright © 1990 by American Diabetes Association

ARTICLES

Molecular biology for nonmolecular biologists

JM Chirgwin
Department of Medicine, University of Texas Health Science Center, San Antonio 78284.

Molecular biology offers various powerful tools for understanding the etiology of diabetes mellitus. These methods can be understood by nonmolecular biologists. Topics briefly introduced include 1) control of gene expression, 2) cloning of genes, 3) how gene promoters work, 4) transgenic mice, 5) mutagenesis in vitro, 6) human molecular genetics, and 7) the new powerful polymerase chain-reaction technique, which greatly simplifies many of the other methods.
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Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1990 by the American Diabetes Association.