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Diabetes Care, Vol 15, Issue 7 912-914, Copyright © 1992 by American Diabetes Association

ARTICLES

Association of waist-hip ratio with diabetes mellitus. Strength and possible modifiers

MI Schmidt, BB Duncan, LH Canani, C Karohl and L Chambless
Research Support Group, School of Medicine, Federal University of Rio Grande do Sul, Brazil.

OBJECTIVE--To characterize the association between central obesity, as measured by the waist-hip ratio (WHR), and non-insulin-dependent diabetes mellitus (NIDDM), considering the effects of sex, age, overall obesity, and family history of diabetes. RESEARCH DESIGN AND METHODS--Case-control study nested within a community-based survey. We selected 151 subjects with NIDDM and 301 nondiabetic control subjects as a systematic sample of survey screening negative individuals. RESULTS--Odds ratios for NIDDM, comparing a high WHR (greater than or equal to 0.926 for men, greater than or equal to 0.83 for women) to a low WHR were 4.72 with a 95% confidence interval of 2.39-9.34, and 2.17 with a 95% confidence interval of 1.03-4.58, for women and men, respectively, controlling for age, overall obesity, and a family history of diabetes. Women with high WHRs in the presence of these risk factors are notably at risk for diabetes. CONCLUSION--Central obesity, as measured by the WHR, is importantly and independently associated with NIDDM.
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Copyright © 1992 by the American Diabetes Association.