Diabetes Care, Vol 16, Issue 12 1606-1611, Copyright © 1993 by American Diabetes Association
An epidemic of childhood diabetes in the United States? Evidence from Allegheny County, Pennsylvania.Pittsburgh Diabetes Epidemiology Research Group
TM Dokheel
Pittsburgh Diabetes Epidemiology Research Group, Pennsylvania.
OBJECTIVE--To evaluate IDDM trends in Allegheny County, Pennsylvania, from
1965 to 1989. RESEARCH DESIGN AND METHODS--A population-based registry
established in 1976--the Allegheny County Registry--was used for this study
through a retrospective chart review of all cases diagnosed in the county
from 1965. Through this registry, cases of IDDM patients < 20 yr of age
were identified. In addition, pediatricians in the county were contacted
about IDDM cases they diagnosed between 1965 and 1989 in individuals <
20 yr of age. RESULTS--For the first time a major increase in IDDM was seen
(1985-1989). This increase in IDDM was heterogenous with the rise for males
being double that for females. The increase for non-white males was
considerably greater than that seen for white males, and an exceptionally
large increase in the youngest age-group (0-4 yr of age) was observed.
CONCLUSIONS--Ecological analyses indicated an association between chicken
pox infection and IDDM, and this suggested that at least part of the rise
may be of an infectious origin.