Diabetes Care, Vol 16, Issue 2 426-428, Copyright © 1993 by American Diabetes Association

ARTICLES

Effect of cold remedies on metabolic control of NIDDM

HJ LeMar and WJ Georgitis
Department of Medicine, Fitzsimons Army Medical Center, Aurora, Colorado 80045-5001.

OBJECTIVE--To compare the effects of two cough syrup formulations (one with sugar and alcohol and one without) on the metabolic control of NIDDM. RESEARCH DESIGN AND METHODS--A prospective, blinded cross-over study was performed at the Endocrinology Clinic of a U.S. Army Medical Center on 20 volunteers with NIDDM, treated with diet alone or diet plus an oral hypoglycemic agent. After a 7-day lead-in period, patients took 3-day courses of each cough syrup (10 ml 4 times/day) with an intervening 4-day wash-out period. Fasting and postprandial blood glucose and lipids before and immediately after each course were compared. RESULTS--No differences in pretherapy and posttherapy values were found with either formula. Values taken after the sugar- and alcohol-containing formula were not different from those taken after the alcohol- and sugar-free formula. CONCLUSIONS--We conclude that patients with NIDDM can take standard daytime cough formulas, in short courses of standard doses, without adverse effect on blood glucose or lipids.
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