Diabetes Care, Vol 17, Issue 10 1154-1157, Copyright © 1994 by American Diabetes Association
Perinatal determinants among children who later develop IDDM
T Bock, CR Pedersen, A Volund, CS Pallesen and K Buschard
Bartholin Instituttet, Kobenhavns Kommunehospital, Copenhagen, Denmark.
OBJECTIVE--The aim of this study was to investigate whether children who
develop insulin-dependent diabetes mellitus (IDDM) differ in some aspects
from a matched control group at the time of birth. RESEARCH DESIGN AND
METHODS--We studied all children who were born in Denmark during the period
1973-1977 and admitted to a Danish hospital with a diagnosis of IDDM during
1978-1989. The study was conducted by combining two nationwide registries,
The National Patient Registry and The Birth Registry. RESULTS--The criteria
were fulfilled by 837 children. Data regarding the age of the parents, the
number of previous pregnancies of the mother, the month of birth, and the
birth weight and length of the children who developed IDDM were compared
with the data of an age- and sex-matched control group of 837 children
without IDDM. We did not detect any significant differences between the two
groups with respect to the parameters studied. CONCLUSIONS--No differences
in perinatal determinants could be demonstrated among Danish children who
develop IDDM compared with children without diabetes.