Diabetes Care, Vol 17, Issue 12 1488-1490, Copyright © 1994 by American Diabetes Association
Relationship between dairy product consumption and incidence of IDDM in childhood in Italy
D Fava, RD Leslie and P Pozzilli
Cattedra di Endocrinologia, University of Rome, La Sapienza, Italy.
OBJECTIVE--To test the hypothesis that the consumption of dairy products,
including fluid cows' milk and cheese, is related to the incidence of
insulin-dependent diabetes mellitus (IDDM), we correlated incidence rates
in children 0-14 years of age with cows' milk and cheese consumption in
nine regions of a single country, Italy. RESEARCH DESIGN AND METHODS--Data
on the incidence of IDDM were derived from the only nine Italian regions
where primary and secondary sources of ascertainment were available for
1991. Data on fluid cows' milk and cheese consumption in the corresponding
year in each region were obtained from the National Institute of
Statistics. RESULTS--The correlation between fluid milk consumption and
incidence of IDDM in Italy was 0.84 (P < 0.004, Poisson regression
analysis). Cheese consumption was not related to IDDM incidence.
CONCLUSIONS--The results indicate that there is a relationship, even in a
single country, between dairy product consumption and the incidence of IDDM
that is confined to fluid milk consumption. Cows' milk may contain a
triggering factor for the development of diabetes, but the high incidence
of IDDM in Sardinia and in other countries worldwide cannot be explained
simply by the quantity of fluid cows' milk consumed.