Diabetes Care, Vol 18, Issue 6 858-861, Copyright © 1995 by American Diabetes Association
Symptoms of hypoglycemia in children with IDDM
RJ McCrimmon, AE Gold, IJ Deary, CJ Kelnar and BM Frier
Department of Diabetes, University of Edinburgh, Scotland.
OBJECTIVE--To examine the symptoms of hypoglycemia in children with
insulin-dependent diabetes, from the perspective both of the child and of
the child's parents, and to compare the symptom reporting of the diabetic
children with that of adult diabetic patients. RESEARCH DESIGN AND
METHODS--Interviews were conducted with 100 parents and 43 of their
children. The frequency and intensity of symptoms of hypoglycemia were
documented using a structured interview and classified into groups using
Principal Components Analysis (PCA). RESULTS--Diabetic children and their
parents showed close agreement concerning the relative frequency and the
intensity of symptoms reported. PCA of the symptom reports showed that
diabetic children and their parents identified the same distinct subgroups
of hypoglycemia-related symptoms: behavioral disturbance and
autonomic-neuroglycopenic subgroups. CONCLUSIONS--Hypoglycemic symptoms in
children with diabetes clearly differ from those experienced by
insulin-treated adults and, in particular, include behavioral changes as
primary features of a low blood glucose. These observations have important
implications for parental education on hypoglycemia.