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Diabetes Care, Vol 20, Issue 4 610-613, Copyright © 1997 by American Diabetes Association

ARTICLES

Catheter survival during long-term insulin therapy with an implanted programmable pump. The Implantable Insulin Pump Trial Study Group

M Scavini, L Galli, S Reich, RP Eaton, MA Charles and FL Dunn
Istituto Scientifico H San Raffaele, Milan, Italy. scavinm@mihsra.hsr.it

OBJECTIVE: To survey catheter complications and to analyze catheter survival during long-term intraperitoneal and intravenous insulin therapy with an implanted programmable pump with a sideport. RESEARCH DESIGN AND METHODS: Catheter occlusions were documented by measuring dynamic catheter resistance. Catheter migrations or breaks were demonstrated by X ray. When flushing the catheter with buffer solution through the sideport failed to clear the occlusion, catheters were replaced or laparoscopy was performed for the excision of fibrous tissue growth. Broken or migrated catheters were replaced. RESULTS: Occlusions were the most common catheter complications, and the majority of them (79% intraperitoneal and 84% intravenous) were cleared by flushing the catheter. Survival at 3 years was significantly higher for intraperitoneal catheters compared with intravenous catheters (60% intraperitoneal and 22% intravenous). CONCLUSIONS: Nonsurgical management of catheter occlusions contributed to extend catheter lifetime. Intraperitoneal catheters have a lower morbidity and a higher survival than intravenous catheters.
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L. Kessler, S. Tritschler, A. Bohbot, S. Sigrist, V. Karsten, S. Boivin, P. Dufour, A. Belcourt, and M. Pinget
Macrophage Activation in Type 1 Diabetic Patients With Catheter Obstruction During Peritoneal Insulin Delivery With an Implantable Pump
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[Abstract] [Full Text]


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Copyright © 1997 by the American Diabetes Association.