|
 |
|
|||||||
|
|||||||||
© 2002 by the American Diabetes Association, Inc.
Epidemiology/Health Services/Psychosocial Research |
The Epidemiology of Type 1 Diabetes in Children in Philadelphia 1990–1994
Evidence of an epidemic
1 School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania
2 Department of Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania
3 The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
OBJECTIVE—To determine the epidemiology of type 1 diabetes in children in Philadelphia from 1990 to 1994, and to identify whether an epidemic occurred during that time period.
RESEARCH DESIGN AND METHODS—This is a descriptive epidemiological study using a retrospective population-based registry in Philadelphia, PA, a city with large white, African-American, and Hispanic (Puerto Rican) populations. All hospitals in Philadelphia that admit children were identified. All charts meeting the following criteria were reviewed: 1) newly diagnosed type 1 diabetes, 2) children 0–14 years of age, 3) children residing in Philadelphia at the time of diagnosis, and 4) those diagnosed from 1 January 1990 to 31 December 1994. Standard type 1 diabetes registry data were abstracted from the charts. Ascertainment of the completeness of the hospital registry was validated by data from the Philadelphia School District. Communicable disease records were reviewed to identify epidemics from 1987 to 1995.
RESULTS—A total of 209 cases were identified, and the combined hospital and school registry was determined to be 96% complete. The overall age-adjusted incidence rate in Philadelphia was 13.3/100,000/year. The highest rate by race continues to be in the Hispanic population (15.5). The incidence in African-American children has increased markedly (12.8), particularly in the 10- to 14-year age-group (22.9). An epidemic of type 1 diabetes occurred from January to June 1993, 
2 years after a measles epidemic in Philadelphia.
CONCLUSIONS—The overall incidence of type 1 diabetes in Philadelphia is similar to other U.S. registries. The incidence in the Hispanic population continues to be among the highest of any U.S. ethnic group. The marked increase in incidence in the African-American population may be due in part to misclassification of cases actually having type 2 diabetes. The 1993 epidemic may have been due to ß-cell autoimmunity triggered by the measles virus.
CiteULike 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  J. M. Lee, M. J. Okumura, G. L. Freed, R. K. Menon, and M. M. Davis Trends in Hospitalizations for Diabetes Among Children and Young Adults: United States, 1993 2004 Diabetes Care, December 1, 2007; 30(12): 3035 - 3039. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 The Writing Group for the SEARCH for Diabetes in Y Incidence of Diabetes in Youth in the United States JAMA, June 27, 2007; 297(24): 2716 - 2724. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Vehik, R. F. Hamman, D. Lezotte, J. M. Norris, G. Klingensmith, C. Bloch, M. Rewers, and D. Dabelea Increasing Incidence of Type 1 Diabetes in 0- to 17-Year-Old Colorado Youth Diabetes Care, March 1, 2007; 30(3): 503 - 509. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. H. Lipman, A. F. Jawad, K. M. Murphy, A. Tuttle, R. L. Thompson, S. J. Ratcliffe, and L. E. Levitt Katz Incidence of Type 1 Diabetes in Philadelphia Is Higher in Black Than White Children From 1995 to 1999: Epidemic or misclassification? Diabetes Care, November 1, 2006; 29(11): 2391 - 2395. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Lee, W. H. Herman, M. L. McPheeters, and J. G. Gurney An Epidemiologic Profile of Children With Diabetes in the U.S. Diabetes Care, February 1, 2006; 29(2): 420 - 421. [Full Text] [PDF]
|
|
|
|
 |
|
 J. Lee The Changing Epidemiology of Childhood Diabetes AAP Grand Rounds, February 1, 2006; 15(2): 18 - 19. [Full Text] [PDF]
|
|
|
|
|
|
R. S. Suri, W. F. Clark, N. Barrowman, J. L. Mahon, H. R. Thiessen-Philbrook, M. P. Rosas-Arellano, K. Zarnke, J. S. Garland, and A. X. Garg Diabetes During Diarrhea-Associated Hemolytic Uremic Syndrome: A systematic review and meta-analysis Diabetes Care, October 1, 2005; 28(10): 2556 - 2562. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. T. Rhodes, L. R. Ferrari, and J. I. Wolfsdorf Perioperative Management of Pediatric Surgical Patients with Diabetes Mellitus Anesth. Analg., October 1, 2005; 101(4): 986 - 999. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Alba, M. C. Puertas, J. Carrillo, R. Planas, R. Ampudia, X. Pastor, F. Bosch, R. Pujol-Borrell, J. Verdaguer, and M. Vives-Pi IFN{beta} Accelerates Autoimmune Type 1 Diabetes in Nonobese Diabetic Mice and Breaks the Tolerance to {beta} Cells in Nondiabetes-Prone Mice J. Immunol., December 1, 2004; 173(11): 6667 - 6675. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Sullivan-Bolyai, M. Grey, J. Deatrick, P. Gruppuso, P. Giraitis, and W. Tamborlane Helping Other Mothers Effectively Work At Raising Young Children With Type 1 Diabetes The Diabetes Educator, May 1, 2004; 30(3): 476 - 484. [PDF]
|
|
|
|
|
|
I. M. Libman, M. Pietropaolo, S. A. Arslanian, R. E. LaPorte, and D. J. Becker Changing Prevalence of Overweight Children and Adolescents at Onset of Insulin-Treated Diabetes Diabetes Care, October 1, 2003; 26(10): 2871 - 2875. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. M. Libman, M. Pietropaolo, S. A. Arslanian, R. E. LaPorte, and D. J. Becker Evidence for Heterogeneous Pathogenesis of Insulin-Treated Diabetes in Black and White Children Diabetes Care, October 1, 2003; 26(10): 2876 - 2882. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| Diabetes | Diabetes Care | Clinical Diabetes | Diabetes Spectrum |