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Diabetes Care 27:1088-1094, 2004
© 2004 by the American Diabetes Association, Inc.


Emerging Treatments and Technologies
Original Article

Telecare for Patients With Type 1 Diabetes and Inadequate Glycemic Control

A randomized controlled trial and meta-analysis

Victor M. Montori, MD, MSC1, Pamela K. Helgemoe, RN1, Gordon H. Guyatt, MD, MSC2,3, Diana S. Dean, MD1, Teresa W. Leung, BHSC4, Steven A. Smith, MD1 and Yogish C. Kudva, MD1

1 Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Mayo Clinic, Rochester, Minnesota
2 Department of Clinical Epidemiology, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
3 Department of Biostatistics and Medicine, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
4 Bachelor of Health Sciences Program, McMaster University, Hamilton, Ontario, Canada

Address correspondence and reprint requests to Yogish C. Kudva, MD, Mayo W18, 200 1st St. SW, Rochester, MN 55905. E-mail: kudva.yogish{at}mayo.edu

OBJECTIVE—To determine the efficacy of telecare (modem transmission of glucometer data and clinician feedback) to support intensive insulin therapy in patients with type 1 diabetes and inadequate glycemic control.

RESEARCH DESIGN AND METHODS—Thirty-one patients with type 1 diabetes on intensive insulin therapy and with HbA1c >7.8% were randomized to telecare (glucometer transmission with feedback) or control (glucometer transmission without feedback) for 6 months. The primary end point was 6-month HbA1c. To place our findings in context, we pooled HbA1c change from baseline reported in randomized trials of telecare identified in a systematic review of the literature.

RESULTS—Compared with the control group, telecare patients had a significantly lower 6-month HbA1c (8.2 vs. 7.8%, P = 0.03, after accounting for HbA1c at baseline) and a nonsignificant fourfold greater chance of achieving 6-month HbA1c <=7% (29 vs. 7%; risk difference 21.9%, 95% CI –4.7 to 50.5). Nurses spent 50 more min/patient giving feedback on the phone with telecare patients than with control patients. Meta-analysis of seven randomized trials of adult patients with type 1 diabetes found a 0.4% difference (95% CI 0–0.8) in HbA1c mean change from baseline between the telecare and control groups.

CONCLUSIONS—Telecare is associated with small effects on glycemic control in patients with type 1 diabetes on intensive insulin therapy but with inadequate glycemic control.

Abbreviations: DCCT, Diabetes Control and Complications Trial • IQR, interquartile range • SDIS, Stockholm Diabetes Intervention Study • SDSCA, Summary of Diabetes Self-Care Activities


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