HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Oh, J.-Y. Articles by Barrett-Connor, E. Search for Related Content PubMed PubMed Citation Articles by Oh, J.-Y. Articles by Barrett-Connor, E. Social Bookmarking                What's this?

Prevalence and Factor Analysis of Metabolic Syndrome in an Urban Korean Population

¹ Division of Endocrinology and Metabolism, Department of Internal Medicine, Ewha Womans University Medical College, Seoul, Korea
² Division of Epidemiology, Department of Family and Preventive Medicine, University of California, San Diego, California

Address correspondence and reprint requests to Dr. Jee-Young Oh, Division of Endocrinology and Metabolism Department of Internal Medicine, Ewha Womans University Mokdong Hospital, 911-1 Mokdong Yangcheon-Ku, Seoul, Korea 158-710. E-mail: jyoh{at}ewha.ac.kr

OBJECTIVE—The aim of this study was to explore the prevalence and pattern of the metabolic syndrome and its association with hyperinsulinemia in an urban Korean population of 269 men and 505 women.

RESEARCH DESIGN AND METHODS—The National Cholesterol Education Program Adult Treatment Panel (ATP) III guidelines were used to calculate the sex-specific prevalence of the metabolic syndrome. After excluding individuals taking medication for hypertension, diabetes, or dyslipidemia, we used factor analysis to examine the pattern of the metabolic syndrome in 206 men and 449 women.

RESULTS—The prevalence of metabolic syndrome was 16.0% in men and 10.7% in women aged 30–80 years. However, ATP III criteria for central obesity are not optimal for an Asian-Pacific population; when waist circumference is reduced from 102 to 90 cm in men and 88 to 80 cm in women, the prevalence of the metabolic syndrome increased to 29.0 and 16.8%, respectively. Sex-specific factor analysis showed four factors in men (obesity, glucose intolerance, hypertension, and dyslipidemia) and three in women (obesity-hypertension, glucose intolerance, and obesity-dyslipidemia). Insulin resistance estimated from fasting insulin levels clustered with three of the four factors in men and two of the three factors in women. By ATP III or Asian-Pacific waist circumference criteria, the prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance, which was estimated by a homeostasis model assessment.

CONCLUSIONS—The metabolic syndrome is common in an urban Korean population when using Asian-Pacific waist criteria. The prevalence of the metabolic syndrome increased with increasing tertiles of insulin resistance.

Abbreviations: ATP, Adult Treatment Panel • HOMA, homeostasis model assessment • PAI-1, plasminogen activator inhibitor-1

CiteULike    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

				A. Misra and L. Khurana Obesity and the Metabolic Syndrome in Developing Countries J. Clin. Endocrinol. Metab., November 1, 2008; 93(11_Supplement_1): s9 - s30. [Abstract] [Full Text] [PDF]

				M. Hassinen, T. A. Lakka, K. Savonen, H. Litmanen, L. Kiviaho, D. E. Laaksonen, P. Komulainen, and R. Rauramaa Cardiorespiratory Fitness as a Feature of Metabolic Syndrome in Older Men and Women: The Dose-Responses to Exercise Training Study (DR's EXTRA) Diabetes Care, June 1, 2008; 31(6): 1242 - 1247. [Abstract] [Full Text] [PDF]

				H. M. Kim, J. Park, S. Y. Ryu, and J. Kim The Effect of Menopause on the Metabolic Syndrome Among Korean Women: The Korean National Health and Nutrition Examination Survey, 2001 Diabetes Care, March 1, 2007; 30(3): 701 - 706. [Abstract] [Full Text] [PDF]

				G. M. Reaven The Metabolic Syndrome: Requiescat in Pace Clin. Chem., June 1, 2005; 51(6): 931 - 938. [Abstract] [Full Text] [PDF]

				THE DECODE STUDY GROUP and Q. Qiao Comparison of three different definitions for the metabolic syndrome in non-diabetic Europeans The British Journal of Diabetes & Vascular Disease, May 1, 2005; 5(3): 161 - 168. [Abstract] [PDF]

				P. Barter Role of nicotinic acid in raising high-density lipoprotein cholesterol (HDL-C) to reduce cardiovascular risk: an Asian/Pacific consensus: The Pan-Asian Consensus Panel On Hdl-C The British Journal of Diabetes & Vascular Disease, March 1, 2005; 5(2_suppl): S1 - S15. [Abstract] [PDF]