HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager patientINFORMation Request Permissions Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Mayer-Davis, E. J. Articles by Gillman, M. W. Search for Related Content PubMed PubMed Citation Articles by Mayer-Davis, E. J. Articles by Gillman, M. W. Social Bookmarking                What's this?

Breast-Feeding and Risk for Childhood Obesity

Does maternal diabetes or obesity status matter?

¹ Center for Research in Nutrition and Health Disparities, Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina
² Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts
³ Channing Laboratory, Brigham and Women’s Hospital, Boston, Massachusetts
⁴ Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts
⁵ Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts

Address correspondence and reprint requests to Elizabeth J. Mayer-Davis, PhD, Center for Research in Nutrition and Health Disparities, University of South Carolina, Arnold School of Public Health, 2718 Middleburg Dr., Columbia, SC 29208. E-mail: ejmayer{at}gwm.sc.edu

OBJECTIVE— We sought to evaluate whether maternal diabetes or weight status attenuates a previously reported beneficial effect of breast-feeding on childhood obesity.

RESEARCH DESIGN AND METHODS— Growing Up Today Study (GUTS) participants were offspring of women who participated in the Nurses’ Health Study II. In the present study, 15,253 girls and boys (aged 9–14 years in 1996) were included. Maternal diabetes and weight status and infant feeding were obtained by maternal self-report. We defined maternal overweight as BMI 25 kg/m². Childhood obesity, from self-reported height and weight, was based on the Centers for Disease Control and Prevention definitions as normal, at risk for overweight, or overweight. Maternal status categories were nondiabetes/normal weight, nondiabetes/overweight, or diabetes. Logistic regression models used generalized estimating equations to account for nonindependence between siblings.

RESULTS— For all subjects combined, breast-feeding was associated with reduced overweight (compared with normal weight) in childhood. Compared with exclusive use of formula, the odds ratio (OR) for exclusive breast-feeding was 0.66 (95% CI 0.53–0.82), adjusted for age, sex, and Tanner stage. Results did not differ according to maternal status (nondiabetes/normal weight OR 0.73 [95% CI 0.49–1.09]; nondiabetes/overweight 0.75 [0.57–0.99]; and diabetes 0.62 [0.24–1.60]). Further adjustment for potential confounders attenuated results, but results remained consistent across strata of maternal status (P value for interaction was 0.50).

CONCLUSIONS— Breast-feeding was inversely associated with childhood obesity regardless of maternal diabetes status or weight status. These data provide support for all mothers to breast-feed their infants to reduce the risk for childhood overweight.

Abbreviations: GUTS, Growing Up Today Study

CiteULike    Del.icio.us    Digg    Reddit    Technorati    What's this?

Find additional patient-related information at:

More Evidence That Breast-Feeding Lowers Risk for Childhood Obesity

This article has been cited by other articles:

				A. E Buyken, N. Karaolis-Danckert, A. Gunther, and M. Kersting Effects of breastfeeding on health outcomes in childhood: beyond dose-response relations Am. J. Clinical Nutrition, June 1, 2008; 87(6): 1964 - 1965. [Full Text] [PDF]

				R. Carvalho, E. Johnson, M. Kozlosky, and A. O. Scheimann Clinical Profile of the Overweight Child in the New Millennium Clinical Pediatrics, June 1, 2008; 47(5): 476 - 482. [Abstract] [PDF]

				E. J. Mayer-Davis, D. Dabelea, A. P. Lamichhane, R. B. D'Agostino Jr., A. D. Liese, J. Thomas, R. E. McKeown, and R. F. Hamman Breast-Feeding and Type 2 Diabetes in the Youth of Three Ethnic Groups: The SEARCH for Diabetes in Youth Case-Control Study Diabetes Care, March 1, 2008; 31(3): 470 - 475. [Abstract] [Full Text] [PDF]

				L. DeMattia and S. Lee Denney Childhood Obesity Prevention: Successful Community-Based Efforts The ANNALS of the American Academy of Political and Social Science, January 1, 2008; 615(1): 83 - 99. [Abstract] [PDF]

				M Sellwood and A Huertas-Ceballos Review of NICE guidelines on routine postnatal infant care Arch. Dis. Child. Fetal Neonatal Ed., January 1, 2008; 93(1): F10 - F13. [Full Text] [PDF]

				C.-D. Walker A Suckling Feast: Not So Hot After All Endocrinology, September 1, 2007; 148(9): 4147 - 4149. [Full Text] [PDF]

				M. Talim Breast-Feeding and Risk for Childhood Obesity: Response to Mayer-Davis et al. Diabetes Care, February 1, 2007; 30(2): 451 - 451. [Full Text] [PDF]

				E. J. Mayer-Davis, S. L. Rifas-Shiman, L. Zhou, F. B. Hu, G. A. Colditz, and M. W. Gillman Breast-Feeding and Risk for Childhood Obesity: Response to Plagemann et al. Diabetes Care, February 1, 2007; 30(2): 452 - 452. [Full Text] [PDF]

				A. Plagemann, T. Harder, E. Rodekamp, and J. W. Dudenhausen Breast-Feeding and Risk for Childhood Obesity: Response to Mayer-Davis et al. Diabetes Care, February 1, 2007; 30(2): 451 - 452. [Full Text] [PDF]