Diabetes Care, Vol 3, Issue 2 207-213, Copyright © 1980 by American Diabetes Association
Peripheral vascular disease in diabetes mellitus and its relation to cardiovascular risk factors: screening with the doppler ultrasonic technique
HU Janka, E Standl and H Mehnert
Data of 623 nonselected diabetic outpatients are presented who were
screened for peripheral vascular disease (PVD) and for cardiovascular risk
factors. PVD was diagnosed in 15.9% of the diabetic patients (14.4% women
and 18.0% men). Nine percent of the patients had signs of marked
mediasclerosis at the ankle level. Multivariate statistical analysis
revealed that PVD was closely associated with systolic hypertension and
also with the duration of diabetes, a relationship that was highly
significant (P less than 0.001) for the peripheral type (below the knee) of
PVD. Diabetic patients with arterial disease at the pelvic or femoral site
exhibited a higher number of cardiovascular risk factors. In contrast, in
patients with the peripheral type, significantly higher blood glucose
values were found. Therefore, the quality of metabolic control may play an
important part in the development of this form of diabetic macroangiopathy.