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Published online July 31, 2007
Diabetes Care 30:2832-2837, 2007
DOI: 10.2337/dc07-0777
© 2007 by the American Diabetes Association
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Clinical Care/Education/Nutrition/Psychosocial Research
Original Research

Effectiveness of a Self-Management Intervention in Patients With Screen-Detected Type 2 Diabetes

Bart Thoolen, PHD1, Denise De Ridder, PHD1, Jozien Bensing, PHD1,2, Cora Maas, PHD3, Simon Griffin, MD, PHD4, Kees Gorter, MD, PHD5 and Guy Rutten, MD, PHD5

1 Department of Clinical and Health Psychology, Utrecht University, Utrecht, the Netherlands
2 NIVEL: Netherlands Institute for Health Services Research, Utrecht, the Netherlands
3 Department of Methodology and Statistics, Utrecht University, Utrecht, the Netherlands
4 MRC Epidemiology Unit, Cambridge, U.K
5 Julius Center for Health Sciences and Primary Care, Utrecht, the Netherlands

Address correspondence and reprint requests to Bart Thoolen, Department of Clinical and Health Psychology, Utrecht University, P.O. Box 80.140, 3508 TC Utrecht, Netherlands. E-mail: b.j.thoolen{at}uu.nl

OBJECTIVE—To examine the effectiveness of a theory-driven self-management course in reducing cardiovascular risk in patients with screen-detected type 2 diabetes, taking ongoing medical treatment into account.

RESEARCH DESIGN AND METHODS—A total of 196 screen-detected patients, receiving either intensive pharmacological or usual-care treatment since diagnosis (3–33 months previously), were subsequently randomized to a control or intervention condition (self-management course). A 2 x 2 factorial design evaluated the behavioral intervention (self-management course versus control) nested within the medical treatment (intensive versus usualcare), using multilevel regression modeling to analyze changes in patients’ BMI, A1C, blood pressure (BP), and lipid profiles over 12 months, from the start of the 3-month course to 9-month follow-up.

RESULTS—The self-management course significantly reduced BMI (–0.77 kg/m2) and systolic BP (–6.2 mmHg) up until the 9-month follow-up, regardless of medical treatment. However, intensive medical treatment was also independently associated with lower BP, A1C, total cholesterol, and LDL before the course and further improvements in systolic BP (–4.7 mmHg). Patients receiving both intensive medical treatment and the self-management course therefore had the best outcomes.

CONCLUSIONS—This self-management course was effective in achieving sustained reductions in weight and BP, independent of medical treatment. A combination of behavioral and medical interventions is particularly effective in reducing cardiovascular risk in newly diagnosed patients.

Abbreviations: BP, blood pressure • ADDITION, Anglo-Danish-Dutch Study of Intensive Treatment in People With Screen-Detected Type 2 Diabetes in Primary Care


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