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Nonalcoholic Fatty Liver Disease and Insulin Resistance in Youth

Zachary T. Bloomgarden, MD, is a practicing endocrinologist in New York, New York, and is affiliated with the Division of Endocrinology, Mount Sinai School of Medicine, New York, New York

ABSTRACT

Perspectives on the News commentaries are now part of a new, free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, is designating this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate. The Mount Sinai School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Abbreviations: ALT, alanine transaminase • AST, aspartate transaminase • CVD, cardiovascular disease • FFA, free fatty acid • IGT, impaired glucose tolerance • IMCL, intramyocellular lipid • IRS, insulin resistance syndrome • IUGR, intrauterine growth retardation • NAFLD, nonalcoholic fatty liver disease • NASH, nonalcoholic steatohepatitis • NHANES, National Health and Nutrition Examination Survey • SREBP, sterol regulatory element–binding protein

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