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Published online December 10, 2007
Diabetes Care 31:498-500, 2008
DOI: 10.2337/dc07-2058
© 2008 by the American Diabetes Association
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Epidemiology/Health Services Research
Original Research

Incidence and Determinants of Carpal Tunnel Decompression Surgery in Type 2 Diabetes

The Fremantle Diabetes Study

Ashley Makepeace, MBBS, Wendy A. Davis, MPH, PHD, David G. Bruce, MD, FRACP and Timothy M.E. Davis, PHD, FRACP

From the University of Western Australia, Fremantle Hospital, Fremantle, Western Australia

Address correspondence and reprint requests to Professor T.M.E. Davis, University of Western Australia, Fremantle Hospital, P.O. Box 480, Fremantle, Western Australia 6959, Australia. E-mail: tdavis{at}cyllene.uwa.edu.au

To examine the incidence and predictors of carpal tunnel decompression (CTD) in community-based patients with type 2 diabetes, we studied 1,284 type 2 diabetic participants (mean ± SD age 64.1 ± 6.1 years, 49.1% male) in the longitudinal observational Fremantle Diabetes Study who had no history of CTD. A total of 67 participants (5.8%) had a first CTD during 12,109 years (mean 9.4 ± 3.7) of follow-up, an incidence of 5.5 per 1,000 patient-years. This was at least 4.2 times the incidence in the general population (P < 0.001). In Cox proportional hazards analysis, significant independent determinants of first-ever CTD were higher BMI, taking lipid-lowering medication, and being in a stable relationship (P ≤ 0.021). The crude incidence of first CTD is increased in type 2 diabetes and is associated with obesity and sociodemographic/treatment factors that could indicate treatment-seeking behavior including CTD in symptomatic patients.

Abbreviations: WADLS, Western Australia Data Linkage System • CTD, carpal tunnel decompression • CTS, carpal tunnel syndrome • FDS, Fremantle Diabetes Study


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