Diabetes Care
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Diabetes Care, Vol 5, Issue 2 111-113, Copyright © 1982 by American Diabetes Association

ARTICLES

The effect on mortality of low-dose insulin therapy for diabetic ketoacidosis

MC Sheppard and AD Wright

The presentation, treatment, and outcome in 353 episodes of diabetic ketoacidosis have been examined to assess the effect of low-dose insulin therapy on mortality. There were 19 deaths during the period of study, with a mortality rate of 4.4% for patients treated with infrequent large doses of soluble insulin and 4.6% for patients treated with frequent intramuscular injections or continuous infusion of insulin. We conclude that in a center which practices an intensive care approach to the management of diabetic ketoacidosis, the use of a low-dose insulin regimen has not altered mortality.
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Diabetes Diabetes Care Clinical Diabetes Diabetes Spectrum
Copyright © 1982 by the American Diabetes Association.