Diabetes Care
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Diabetes Care, Vol 7, Issue 3 224-227, Copyright © 1984 by American Diabetes Association

ARTICLES

Decreased skin wrinkling in diabetes mellitus

CV Clark, B Pentland, DJ Ewing and BF Clarke

Skin wrinkling, which may be dependent on peripheral autonomic innervation, was assessed in 100 normal and 42 diabetic subjects using a temperature-controlled water bath with immersion of the hands for 30 min. Markedly decreased skin wrinkling was observed in diabetic subjects and in manual workers, but did not correlate with cardiovascular tests of autonomic function, control, type or duration of diabetes, or diabetic complications. The cause of decreased skin wrinkling in people with diabetes is unexplained.
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Copyright © 1984 by the American Diabetes Association.