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Diabetes Care 26:545-546, 2003
© 2003 by the American Diabetes Association, Inc.

Letters: Observations
Letter

Inflammatory Parameters Are Independent Predictors of Severe Epicardial Coronary Stenosis in Asymptomatic Diabetic Patients With Silent Myocardial Ischemia

Christophe Piot, MD1, Annick Fontbonne, MD2, Arianne Sultan, MS3, Manasse Rasamisoa, MS3, Denis Mariano-Goulart, MD4, Jean-Marc Davy, MD1, Louis Monnier, MD3 and Antoine Avignon, MD3

1 Cardiovascular Diseases Department, Montpellier University Hospital, Montpellier, France
2 INSERM, Unit 500, Montpellier, France
3 Metabolic Diseases Department, Montpellier University Hospital, Montpellier, France
4 Nuclear Medicine Department, Montpellier University Hospital, Montpellier, France

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Inflammatory markers (IM) have been associated with the risk of development of coronary artery disease (CAD) in nondiabetic patients (1). So far, no data are available concerning the relationship between angiographically documented CAD and inflammation in the diabetic population. Moreover, recently it has been suggested that in patients with silent myocardial ischemia (SMI), a condition frequently observed in diabetic populations (2), there is a higher production of anti-inflammatory cytokines (3), which suggests that the commonly described association between IM and CAD might not be found . . . [Full Text of this Article]


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Copyright © 2003 by the American Diabetes Association.