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Diabetes Care 28:983-984, 2005
© 2005 by the American Diabetes Association, Inc.

Letters: Observations

Successful Treatment of Insulin Allergy in a 1-Year-Old Infant With Neonatal Diabetes by Lispro and Glargine Insulin

Cengiz Kara, MD, Alev Oguz Kutlu, MD, Olcay Evliyaoglu, MD, Hatice Bilgili, CDE and Nurdan Yildirim, CDE

From the Department of Pediatric Endocrinology, Dr. Sami Ulus Children’s Hospital, Ankara, Turkey

Address correspondence to Cengiz Kara, MD, Konrad Adenauer Cad, no. 19/7 Sancak Mah, 06550, Ankara, Turkey. E-mail: cengizkara68@yahoo.com

The first 20% of the full text of this article appears below.

Systemic insulin allergy is a rare condition and has usually been reported in adults. Human insulin analogs have been proposed for the treatment of insulin allergy (1,2). Here we report a 1-year-old infant with generalized allergy to insulin who has been successfully treated with the insulin analogs lispro and glargine. To our knowledge, this case subject is the youngest child reported with systemic insulin allergy and the only patient who was treated without any adverse event by glargine insulin in infancy.

A neonate girl, the first child of consanguineous parents, was born at full term after uneventful pregnancy. She was small for gestational age with a birth weight of 1,430 g. Although the infant had been fed . . . [Full Text of this Article]


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Copyright © 2005 by the American Diabetes Association.