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Diabetes Care 28:986-987, 2005
© 2005 by the American Diabetes Association, Inc.


Letters: Comments and Responses

Lipids and Glucose in Type 2 Diabetes: What About the ß-Cell and the Mitochondria?

Response to Eldor and Raz

Guenther Boden, MD1 and Markku Laakso, MD2

1 Temple University Health Science Center, General Clinical Research Center, Philadelphia, Pennsylvania
2 Kuopio University Hospital, Kuopio, Finland

Address correspondence to Dr. Guenther Boden, MD, Temple University Health Science Center, General Clinical Research Center, North Broad St., 4W, Philadelphia, PA 19140. E-mail: guenther.boden@tuhs.temple.edu

The first 20% of the full text of this article appears below.

Drs. Eldor and Raz (1) assert that "high levels of FFAs [free fatty acids] have a detrimental effect on ß-cell survival and insulin secretion." We agree, but only in relation to patients who have dysfunctional ß-cells, i.e., patients with pre-diabetes, impaired glucose tolerance, or type 2 diabetes (2–5). . . . [Full Text of this Article]


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Copyright © 2005 by the American Diabetes Association.