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Diabetes Care 28:2084-2085, 2005
© 2005 by the American Diabetes Association, Inc.

Letters: Observations

Use of Glargine Insulin Before and During Pregnancy in a Woman With Type 1 Diabetes and Addison’s Disease

Maria Dolci, Mary Mori and Fabio Baccetti

From the Diabetes Service, Massa e Carrara, Italy

Address correspondence and reprint requests to Fabio Baccetti, Consultant in Endocrinology and Diabetology, Diabetes Service Massa e Carrara, Via Sottomonte 1 54100, Massa e Carrara, Italy. E-mail: f.baccetti@usl1.toscana.it

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We report a case of a 31-year-old Caucasian woman (weight 50 kg, height 148 cm) with type 1 diabetes diagnosed 27 years ago and Addison’s disease discovered 5 years ago, who had a pregnancy with normal outcome treated with lispro and glargine insulin.

For years, the patient has followed a regimen of multiple daily injections of lispro before meals, NPH at bedtime, and 75 mg/day cortone acetate. Her metabolic control has been constantly altered (April 2002 A1C, 8.4%), and she has had frequent episodes of mild and at times severe hypoglycemia, especially at night. At morning, glycemia was often high. When NPH was changed to insulin glargine, hypoglycemic episodes were drastically . . . [Full Text of this Article]


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 Diabetes Spectr.Home page
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Diabetes Spectr, April 1, 2007; 20(2): 94 - 101.
[Abstract] [Full Text] [PDF]


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Copyright © 2005 by the American Diabetes Association.