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Diabetes Care 29:422-423, 2006
DOI: 10.2337/diacare.29.02.06.dc05-1080
© 2006 by the American Diabetes Association
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Pathophysiology/Complications
Brief Report

Hemocue Urine Albumin Point-Of-Care Test Shows Strong Agreement With the Results Obtained With a Large Nephelometer

Gösta Florvall1, Samar Basu, PHD2, Johanna Helmersson, PHD2 and Anders Larsson, MD, PHD1

1 Section of Clinical Chemistry, Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden
2 Section of Clinical Nutrition Research, Department of Public Health and Caring Sciences, Uppsala University Hospital, Uppsala, Sweden

Address correspondence and reprint requests to Anders Larsson, Department of Medical Sciences, University Hospital, S-751 85 Uppsala, Sweden. E-mail: anders.larsson@akademiska.se

Abbreviations: ACR, albumin-to-creatinine ratio • POCT, point-of-care testing

The first 20% of the full text of this article appears below.


   INTRODUCTION
 
There is an increasing incidence of diabetic nephropathy, predominantly in patients with type 2 diabetes (1–3). Persistent microalbuminuria is a sign of ongoing glomerular injury and a strong predictor of clinical nephropathy, and screening for microalbuminuria, the earliest manifestation of diabetic nephropathy, is recommended for all diabetic patients (4).

Point-of-care testing (POCT) offers rapid test results, which facilitate the use of the results to motivate the patient to lifestyle changes and increased compliance (5–7). To achieve good compliance, it is essential that the patient and physician work together and that the patient get regular feedback on the treatment results. The feedback is considered to be more effective if the test results are available during the consultation. This has led to the development of POCT instruments for measuring urine albumin excretion.

The aim of the present study was to evaluate urine albumin analyzed by the HemoCue . . . [Full Text of this Article]


   RESEARCH DESIGN AND METHODS
 
Urine albumin
Statistical calculations

   RESULTS
 
Correlation between urine albumin and ACR assays

   CONCLUSIONS
 

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Copyright © 2006 by the American Diabetes Association.