DOI: 10.2337/diacare.29.02.06.dc05-1931 © 2006 by the American Diabetes Association
Effect of Multifactorial Intervention on Diabetic Macular Edema
1 Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, India Address correspondence to Amod Gupta, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. E-mail: eyepgi@sify.com
Clinical trials (1, 2) have shown that intensive control of blood glucose and hypertension reduce development of clinically significant macular edema (CSME). Elevated HbA1c (A1C) is a risk for persistent CSME (3). Gross proteinuria is associated with a 95% increase in the incidence of macular edema (4). However, the effect of control of systemic factors before focal laser photocoagulation is not known. We aimed to determine whether multifactorial intervention over 46 weeks before focal laser photocoagulation
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