Diabetes Care
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Diabetes Care 29:1178-1179, 2006
DOI: 10.2337/dc06-0106
© 2006 by the American Diabetes Association
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Letters: Observations

Prostatic Cancer, Hypogonadism, and Insulin Resistance

A case report

John A. Kiayias, MD, Eugenia D. Vlachou, PHD, Sofoklis Bakides, MD, Eudokia Petridou, MD and Ilias N. Migdalis, MD

From the Second Department of Internal Medicine, NIMTS Hospital, Athens, Greece

Address correspondence to John A. Kiayias, MD, Agisilaou 72, Sparti 23100, Greece. E-mail: jkiayias@endo.gr

The first 20% of the full text of this article appears below.

A 47-year-old Greek diabetic man presented with erectile dysfunction and a decrease in sexual desire. The patient had type 2 diabetes for the previous 8 years and was on treatment with rosiglitazone and metformin with strict glycemic control (HbA1c 5.8%). No symptoms or signs of neuropathy were present. Hypogonadotrophic hypogonadism was found.

His plasma testosterone level was very low (100 ng/dl [reference range 300–1,000]) and there was no luetinizing hormone response to luetinizing hormone–releasing hormone (LHRH) test. Further work-up with a magnetic resonance imaging scan and hypophyseal function tests did not reveal any space-occupying lesions of the hypothalamic pituitary site.

The process led to the diagnosis of idiopathic hypogonadotropic hypogonadism. On further work-up, the patient was found to have a prostatic carcinoma. . . . [Full Text of this Article]


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Copyright © 2006 by the American Diabetes Association.