Diabetes Care
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Diabetes Care 29:1458 2006
DOI: 10.2337/dc06-0487
© 2006 by the American Diabetes Association
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Letters: Observations

Treatment of Hyperglycemia in a 7-Year-Old Child Diagnosed With Neonatal Diabetes

Eba Hathout, MD1, John Mace, MD1, Graeme I. Bell, PHD2 and Pål R. Njølstad, MD, PHD3,4

1 Department of Pediatrics, Loma Linda University, Loma Linda, California
2 Department of Medicine and Human Genetics, University of Chicago, Chicago, Illinois
3 Department of Clinical Medicine, University of Bergen, Bergen, Norway
4 Department of Pediatrics, Haukeland University Hospital, Bergen, Norway

Address correspondence to Eba Hathout, MD, FAAP, Professor and Chief, Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Loma Linda University, 11175 Campus St., Coleman Pavilion, Room A1120R, Loma Linda, CA 92354. E-mail: ehathout@ahs.llumc.edu

The first 20% of the full text of this article appears below.

Permanent neonatal diabetes is persistent, insulin-requiring hyperglycemia occurring before 1 month of life. Recent studies have identified activating mutations in KCNJ11 encoding the Kir6.2 subunit of the ATP-sensitive K+ channel as a common cause of neonatal diabetes (1,2,3,4,5). These patients can be successfully managed with oral sulfonylureas rather than insulin . . . [Full Text of this Article]


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Copyright © 2006 by the American Diabetes Association.