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Comparison of Anthropometric Characteristics in Predicting the Incidence of Type 2 Diabetes in the EPIC-Potsdam Study

From the Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany

Address correspondence to Matthias B. Schulze, German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany. E-mail: mschulze@mail.dife.de

Abbreviations: EPIC, European Prospective Investigation into Cancer and Nutrition • WHR, waist-to-hip ratio

The first 20% of the full text of this article appears below.

	INTRODUCTION

 
Obesity is a well-established risk factor for type 2 diabetes (1–3). However, while several studies (4–10) suggest that anthropometric measurements that describe central fat distribution are superior in predicting type 2 diabetes compared with measurements of general adiposity, this issue remains controversial (11–14). The aim of this study was to compare different anthropometric measurements and derived estimates of body composition, in particular BMI, waist-to-height ratio, waist-to-hip ratio (WHR), metric index, and percentage body fat, in their ability to predict risk of type 2 diabetes in a large prospective cohort study of men and women.

	RESEARCH DESIGN AND METHODS

 
The European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study includes 27,548 subjects, 16,644 women aged mainly 35–65 years and 10,904 men aged mainly 40–65 years, from the general population of Potsdam, Germany, recruited between 1994 and 1998 (15). The baseline examination included anthropometric measurements (16,17) as well as a personal interview and a questionnaire on prevalent diseases and sociodemographic and lifestyle characteristics. Follow-up questionnaires have been administered every 2–3 years. Response rates for follow-up rounds 1, 2, 3, and 4 were 96, 95, 91, and 90% . . . [Full Text of this Article]

	RESULTS

 

	CONCLUSIONS

 

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