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Diabetes Care 30:e124 2007
DOI: 10.2337/dc07-1246
© 2007 by the American Diabetes Association
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Online Letters: Comments and Responses

Intrauterine Growth Retardation, Insulin Resistance, and Nonalcoholic Fatty Liver Disease in Children

Response to Nobili et al.

Abigail Fraser, MPH1, Shah Ebrahim, DM2, Yoav Ben-Shlomo, PHD1, George Davey Smith, DSC1 and Debbie A. Lawlor, PHD1

1 Social Medicine Department, University of Bristol, Bristol, U.K
2 Epidemiology and Population Health Department, London School of Hygiene and Tropical Medicine, London, U.K

Address correspondence to Abigail Fraser, Social Medicine Department, University of Bristol, Canynge Hall, Whiteladies Road, Bristol BS8 2PR, U.K. E-mail: abigail.fraser@bristol.ac.uk

The first 20% of the full text of this article appears below.

We read with interest the article by Nobili et al. (1), who reported results of a case-control study that demonstrated an association between intrauterine growth retardation (defined as small for gestational age [SGA]) and pediatric nonalcoholic streatohepatitis (nonalcoholic fatty liver disease [NAFLD]).

Nobili et al. (1) compared children with NAFLD with hospital control subjects. The choice of control subjects may result in an underestimate of the association between SGA and NAFLD if . . . [Full Text of this Article]


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G. Marchesini, V. Nobili, and E. Bugianesi
Intrauterine Growth Retardation, Insulin Resistance, and Nonalcoholic Fatty Liver Disease in Children: Response to Fraser et al.
Diabetes Care, November 1, 2007; 30(11): e125 - e125.
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Copyright © 2007 by the American Diabetes Association.