Diabetes Care
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Diabetes Care 30:e95 2007
DOI: 10.2337/dc07-1009
© 2007 by the American Diabetes Association
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Online Letters: Comments and Responses

Prevalence of Nonalcoholic Fatty Liver Disease and Its Association With Cardiovascular Disease Among Type 2 Diabetic Patients

Response to Schindhelm, Heine, and Diamant

Giovanni Targher, MD1,2, Lorenzo Bertolini, MD2 and Christopher Day, MD3

1 Section of Endocrinology, Department of Biomedical and Surgical Sciences, University Hospital of Verona, Verona, Italy
2 Department of Internal Medicine, "Sacro Cuore" Hospital, Negrar, Italy
3 Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, England

Address correspondence to Giovanni Targher, MD, Section of Endocrinology, Department of Biomedical and Surgical Sciences, University Hospital, Ospedale Civile Maggiore, Piazzale Stefani 1, 37126 Verona, Italy. E-mail: giovanni.targher@univr.it

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We appreciate the comments by Schindhelm et al. (1) regarding our recent article reporting the prevalence of nonalcoholic fatty liver disease (NAFLD) and its association with cardiovascular disease (CVD) in a type 2 diabetic population (2). In that study, we found that NAFLD is extremely common in type 2 diabetes and is associated with a higher frequency of manifest CVD. The prevalence of NAFLD was 69.5% among participants, and NAFLD was the most common cause (81.5%) of hepatic steatosis on ultrasound. In contrast, the frequency of hepatic steatosis likely due . . . [Full Text of this Article]


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Copyright © 2007 by the American Diabetes Association.