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Diabetes Care 31:e40 2008
DOI: 10.2337/dc07-2431
© 2008 by the American Diabetes Association
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Online Letters: Comments and Responses

Impact of Autonomic Neuropathy on Left Ventricular Function in Normotensive Type 1 Diabetic Patients: a Tissue Doppler Echocardiographic Study

Response to Karamitsos et al.

Per M. Humpert, MD1, Dimitrios Oikonomou, MD1, Michael Morcos, MD1, Helmut Kuecherer, MD2, Tobias Schilling, MD1, Angelika Bierhaus, PHD1, Peter P. Nawroth, MD1, Hugo A. Katus, MD2 and Grigorios Korosoglou, MD2

1 Department of Medicine I and Clinical Chemistry, Heidelberg University, Heidelberg, Germany
2 Department of Medicine III, Heidelberg University, Heidelberg, Germany

Corresponding author: Dr. Per Humpert, Dept. of Medicine I, Heidelberg University, INF410, 69123 Heidelberg, Germany. E-mail: per.humpert@med.uni-heidelberg.de

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Data from a recent study (1) suggest that autonomic cardiovascular function (ANF) influences left ventricular (LV) diastolic function in patients with type 1 diabetes. Utilizing similar methods, including tissue Doppler imaging (TDI) and echocardiographic phase imaging (EPI) as described (2), we studied 49 type 2 diabetic patients (33 men, 16 women) with normal renal function and LV wall thickness. Five patients had a history of coronary artery disease (CAD), and none had previous myocardial infarction. Patients were screened for ANF as described (3) utilizing a standardized protocol and were divided into groups by tertiles of expiration-to-inspiration ratio . . . [Full Text of this Article]


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This article has been cited by other articles:


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T. D. Karamitsos, H. I. Karvounis, T. Didangelos, G. E. Parcharidis, and D. T. Karamitsos
Impact of Autonomic Neuropathy on Left Ventricular Function in Normotensive Type 1 Diabetic Patients: a Tissue Doppler Echocardiographic Study: Response to Humpert et al.
Diabetes Care, May 1, 2008; 31(5): e41 - e41.
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