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Diabetes Care Publish Ahead of Print published online ahead of print April 27, 2007
DOI: 10.2337/dc06-2402
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Original Research

Body Mass Index versus the Metabolic Syndrome in Relation to Cardiovascular Risk in the Chinese Elderly

Yao He, MD, PhD1,,2, Bin Jiang, MD, PhD3, Jie Wang, MD, PhD4, Kang Feng, MD1, Qing Chang, MD1, Shanxiang Zhu, MPH1, Li Fan, MD5, Xiaoying Li, MD5 and Frank B. Hu, MD, PhD2

1 Institute of Geriatrics, Chinese PLA General Hospital, China
2 Nutrition, Harvard School of Public Health, USA
3 Acupuncture, Chinese PLA General Hospital, China
4 Clinic of PLA Communication, China
5 Geriatric Cardiology, Chinese PLA General Hospital, China

yhe301{at}sina.com

frank.hu{at}channing.harvard.edu

ABSTRACT

OBJECTIVE:To evaluate the associations of body mass index (BMI) versus metabolic syndrome (MS) with cardiovascular diseases (CVD) in Chinese elderly.

RESEACH DESIGN AND METHODS:We conducted a population-based cross-sectional study in an urban elderly sample of 2,334 subjects (943 men and 1,391 women). Subjects were classified by BMI ( ≤ 18.5 kg/m2, < 24 kg/m2, < 28 kg/m2, and ≥ 28 kg/m2), and the presence or absence of MS, which was defined by International Diabetes Federation (IDF) criteria. CVD included clinically diagnosed coronary heart disease (CHD), stroke, and peripheral arterial disease (PAD).

RESULTS:The prevalence of overweight (BMI≥25) and metabolic syndrome according to the IDF criteria was 56.3% (53.9% in men, 57.9% in women) and 46.3% (34.8% in men, 54.1% in women), respectively. Increasing BMI was strongly associated with a higher risk of CHD, stroke, and PAD even after adjusting for MS and other CVD risk factors. Stratified analysis of participants with or without metabolic syndrome showed that BMI was independently associated with CHD, stroke, and PAD.

CONCLUSIONS:Both overweight and MS are highly prevalent in this elderly Chinese population. BMI, as a measure of overall adiposity, is strongly associated with increased prevalence of CVD independent of MS.


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Copyright © 2007 by the American Diabetes Association.