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Diabetes Care Publish Ahead of Print published online ahead of print November 16, 2007
DOI: 10.2337/dc07-1784

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Original Research

The Impact of Diabetes Mellitus on Physical Function in Older People

Alan J. Sinclair, MD1, Simon P. Conroy, MB, ChB2 and Antony J. Bayer, MD3

1University of Bedfordshire
2Nottingham University
3Cardiff University

Sinclair.5{at}btinternet.com

ABSTRACT

Objective: To explore the nature of functional impairment in older people with diabetes

Research design and methods: A population based case-control study, with detailed assessment of diabetes and functional status, was undertaken.

Results: 403 cases and 403 matched controls were studied, median age 75 years, 51% female. Subjects with diabetes had more comorbidities than controls (mean 2.5 v 1.9, p<0.0001) and were more likely to have severe functional impairment (4% v 1%, Barthel score <5, p<0.001). Health status pertaining to physical function was reduced in cases (SF36 60 v 40, p<0.0001). In a multivariate model controlling for age, hypertension, cerebrovascular disease, COPD, cancer, osteoarthritis and dementia, diabetes remained significantly associated with mobility limitation (OR 2.1, p<0.001).

Conclusions: Older people with diabetes have considerable functional impairment associated with reduced health status. This population may benefit from comprehensive geriatric assessment and tailored diabetes management.


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