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An Epidemic of Childhood Diabetes in the United States?: Evidence from Allegheny County, Pennsylvania

  1. Tomadher M Dokheel, MD, PHD and
  2. The Pittsburgh Diabetes Epidemiology Research Group
  1. Pittsburgh Diabetes Epidemiology Research Group Pittsburgh, Pennsylvania
  1. Address correspondence and reprint requests to Ronald LaPorte, PhD, Rangos Research Center, 5th floor, 3460 Fifth Avenue, Pittsburgh, PA 15213.

Abstract

OBJECTIVE To evaluate IDDM trends in Allegheny County, Pennsylvania, from 1965 to 1989.

RESEARCH DESIGN AND METHODS A population-based registry established in 1976—the Allegheny County Registry—was used for this study through a retrospective chart review of all cases diagnosed in the county from 1965. Through this registry, cases of IDDM patients <20 yr of age were identified. In addition, pediatricians in the county were contacted about IDDM cases they diagnosed between 1965 and 1989 in individuals <20 yr of age.

RESULTS For the first time a major increase in IDDM was seen (1985–1989). This increase in IDDM was heterogenous with the rise for males being double that for females. The increase for non-white males was considerably greater than that seen for white males, and an exceptionally large increase in the youngest age-group (0–4 yr of age) was observed.

CONCLUSIONS Ecological analyses indicated an association between chicken pox infection and IDDM, and this suggested that at least part of the rise may be of an infectious origin.

  • Received November 23, 1992.
  • Revision received June 30, 1993.
  • Accepted June 30, 1993.
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This Article

  1. doi: 10.2337/diacare.16.12.1606 Diabetes Care December 1993 vol. 16 no. 12 1606-1611
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