An epidemic of childhood diabetes in the United States? Evidence from Allegheny County, Pennsylvania.Pittsburgh Diabetes Epidemiology Research Group.

Abstract

OBJECTIVE--To evaluate IDDM trends in Allegheny County, Pennsylvania, from 1965 to 1989. RESEARCH DESIGN AND METHODS--A population-based registry established in 1976--the Allegheny County Registry--was used for this study through a retrospective chart review of all cases diagnosed in the county from 1965. Through this registry, cases of IDDM patients < 20 yr of age were identified. In addition, pediatricians in the county were contacted about IDDM cases they diagnosed between 1965 and 1989 in individuals < 20 yr of age. RESULTS--For the first time a major increase in IDDM was seen (1985-1989). This increase in IDDM was heterogenous with the rise for males being double that for females. The increase for non-white males was considerably greater than that seen for white males, and an exceptionally large increase in the youngest age-group (0-4 yr of age) was observed. CONCLUSIONS--Ecological analyses indicated an association between chicken pox infection and IDDM, and this suggested that at least part of the rise may be of an infectious origin.