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Microalbuminuria in NIDDM

  1. Mani M Bashyam, MRCP,
  2. Neil J O'Sullivan, AIMLS,
  3. Habib H Baker, MSC,
  4. Patrick F Duggan, DSC and
  5. Teresa H Mitchell, MD
  1. Departments of Medicine and Biochemistry, Cork Regional Hospital Wilton, Cork, Ireland
  1. Address correspondence and reprint requests to T.H. Mitchell, MD, Consultant Physician, Department of Medicine, Cork Regional Hospital, Wilton, Cork, Ireland.

Abstract

OBJECTIVE To determine an effective screening procedure for microalbuminuria.

RESEARCH DESIGN AND METHODS The prevalence of microalbuminuria in NIDDM patients whose urine was negative on routine Albustix testing was studied. Microalbuminuria was measured in overnight urine samples from 128 NIDDM patients on at least two of three occasions over a 6-mo period. Patients were tested with Micro-Bumintest or Micral-Test.

RESULTS Ten of 128 patients had albumin concentrations ≥ or = 20 mg/L on two or more occasions, 14 patients had A-C ratios ≥ or = 3 mg/M on two or more occasions, and 9 patients had both.

CONCLUSIONS Neither Micro-Bumintest nor Micral-Test is a useful or feasible screening procedure for microalbuminuria.

  • Received June 5, 1992.
  • Revision received November 5, 1992.
  • Accepted November 5, 1992.
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