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Prevalence of Isthmic Lumbar Spondylolisthesis in Nondiabetic Subjects and NIDDM Patients

  1. Lauri Virta, MD,
  2. Tapani Rönnemaa, MD and
  3. Markku Laakso, MD
  1. Rehabilitation Research Centre of Social Insurance Institution Turku
  2. Department of Medicine, University of Turku Turku
  3. Department of Medicine, University of Kuopio Kuopio, Finland
  1. Address correspondence and reprint requests to Lauri Virta, MD, The Rehabilitation Research Centre of Social Insurance Institution, Peltolantie 3, SF-20720 Turku, Finland.

Abstract

OBJECTIVE To compare the prevalence of lumbar spondylolytic spondylolisthesis (LSS) in nondiabetic and diabetic subjects.

RESEARCH DESIGN AND METHODS A cross sectional study of 1,147 randomly selected nondiabetic subjects and 892 non-insulin-dependent diabetes mellitus (NIDDM) patients, 45–64 years of age. LSS was diagnosed radiographically using a lateral view of the lumbosacral spine.

RESULTS No significant difference was seen in the prevalence of LSS between nondiabetic (6.0%) and diabetic (5.7%) subjects. LSS was more frequent in nondiabetic men (7.7%) than in nondiabetic women (4.6%; P = 0.026), whereas diabetic patients showed no significant sex difference in the prevalence of LSS (men 5.6% and women 5.9%).

CONCLUSIONS NIDDM does not predispose one to lumbar spondylolisthesis. However, diabetes seems to abolish the sex difference in the prevalence of LSS observed in nondiabetic populations.

  • Received April 12, 1993.
  • Accepted October 20, 1993.
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