Routine Perioperative Dipyridamole 2O1TI Imaging in Diabetic Patients Undergoing Vascular Surgery: Is it necessary?
- Stuart W Zarich, MD,
- Mylan C Cohen, MD, MPH,
- Stephen E Lane, MD,
- Murray A Mittleman, MD, MPH, DRPH,
- Richard W Nesto, MD,
- Thomas Hill, MD,
- David Campbell, MD and
- Stanley M Lewis, MD
- Cardiovascular Division, Department of Medicine, Department of Radiology, and Department of Surgery, Deaconess Hospital, Harvard Medical School Boston, Massachusetts
- Address correspondence and reprint requests to Stuart W. Zarich, MD, Cardiovascular Division, Deaconess Hospital, 185 Pilgrim Rd., Boston, MA 02215
Abstract
OBJECTIVE To assess the utility of dipyridamole thallium testing in symptomatic and asymptomatic patients with diabetes undergoing vascular surgery.
RESEARCH DESIGN AND METHODS Dipyridamole 201Tl myocardial scmtigraphy was performed preoperatively in 93 consecutive patients with diabetes undergoing peripheral vascular procedures. The utility of clinical and thallium variables in predicting cardiovascular complications was assessed.
RESULTS Two groups of patients were identified: group A (36 patients) without clinical evidence of cardiac disease and group B (57 patients) with clinical evidence of cardiac disease. Dipyridamole thallium scans were abnormal in 21 of 36 (58%) of group A patients compared with 53 of 57 (93%) of group B patients (P < 0.0001). Compared with group B patients with perfusion defects, group A patients with perfusion abnormalities tended to have fewer defects per scan (2.7 ± 1.5 vs. 3.6 ± 1.9, P = 0.05). No perioperative cardiac complications occurred in group A patients while perioperative cardiac complications occurred in 9 of 57 (16%, 95% CI 7-28%) group B patients (P = 0.01). For the entire study population, the complication rate was 10%.
CONCLUSIONS Diabetic individuals without clinical markers for coronary artery disease appear to be at low risk for adverse postoperative cardiac events after vascular surgery. Preoperative myocardial perfusion imaging may add little to cardiovascular risk assessment in this subgroup of patients with diabetes.
- Received July 5, 1995.
- Accepted October 26, 1995.
- Copyright © 1996 by the American Diabetes Association











