A Randomized Controlled Trial of Weight Reduction and Exercise for Diabetes Management in Older African-American Subjects
- Tanya D Agurs-Collins, PHD,
- Shiriki K Kumanyika, PHD,
- Thomas R Ten Have, PHD and
- Lucile L Adams-Campbell, PHD
- Pennsylvania State University College of Medicine Division of Epidemiology and Cancer Control Hershey, Pennsylvania
- Pennsylvania State University College of Medicine Howard University Cancer Center Washington, DC Center for Biostatistics and Epidemiology Hershey, Pennsylvania
- Address correspondence and reprint requests to Tanya Agurs-Collins, PhD, Division of Epidemiology and Cancer Control, Howard University Cancer Center, 2041 Georgia Ave., NW, Washington, DC 20006. E-mail: tagurs-collins{at}fac.howard.edu
Abstract
OBJECTIVE To evaluate a weight loss and exercise program designed to improve diabetes management in older African-Americans.
RESEARCH DESIGN AND METHODS Overweight African-Americans (n = 64) ages 55–79 years with NIDDM were randomized to either an intervention (12 weekly group sessions, 1 individual session, and 6 biweekly group sessions) or usual care (1 class and 2 informational mailings). Clinical and behavioral variables were assessed at 0, 3, and 6 months of treatment.
RESULTS Significant net differences in the intervention versus usual care were observed for weight (−2.0 kg, P = 0.006), physical activity, and dietary intake of fat, saturated fat, cholesterol, and nutrition knowledge at 3 months (all P < 0.05) and for weight at 6 months (−2.4 kg; P = 0.006) and mean HbA1c values at 3 and 6 months (respectively, −1.6 and −2.4%, both P < 0.01). After the adjustment for changes in weight and activity, the intervention participants were ∼ twice as likely to have a one unit decrease in HbA1c value as those in usual care. Blood pressure increase sin usual care participants resulted in net differences (intervention minus control) at 3 and 6 months of −3.3 (P = 0.09) and −4.0 (P = 0.05) mmHg diastolic, respectively, and −8.4 (P = 0.06) and −5.9 (P > 0.10) mmHg systolic, respectively. Blood lipid profiles improved more in intervention than usual care participants, but not significantly.
CONCLUSIONS The intervention program was effective in improving glycemic and blood pressure control. The decrease in HbA1c values was generally independent of the relatively modest changes in dietary intake, weight, and activity and may reflect indirect program effects on other aspects of self-care.
- Received November 21, 1996.
- Accepted June 6, 1997.
- Copyright © 1997 by the American Diabetes Association











