Prevalence of Polycystic Ovary Syndrome Among Premenopausal Women With Type 2 Diabetes
- Heather R. Peppard, BS1,
- Jennifer Marfori, BS1,
- Maria J. Iuorno, MD1 and
- John E. Nestler, MD12
- 1Division of Endocrinology and Metabolism, Department of Internal Medicine
- 2Department of Obstetrics and Gynecology, Medical College of Virginia, Virginia Commonwealth University, Richmond, Virginia
Abstract
OBJECTIVE—Women with polycystic ovary syndrome (PCOS) have an increased risk for developing type 2 diabetes. Few studies have assessed women with type 2 diabetes to determine the frequency of PCOS in this population.
RESEARCH DESIGN AND METHODS—To determine the prevalence of PCOS among premenopausal women with type 2 diabetes, we conducted a retrospective cross-sectional prevalence study. We reviewed the medical records of all women seen in the Diabetes Clinic of the Medical College of Virginia Hospitals between January 1995 through February 2000. A diagnosis of PCOS was based on 1) oligomenorrhea, 2) hyperandrogenism (biochemical or clinical), and 3) exclusion of other related disorders.
RESULTS—We reviewed the medical records of 618 women with diabetes and identified 47 women eligible for study. Of the 47 women, 30 consented to an evaluation. Of the 30 women evaluated, 8 were identified as having PCOS (6 women reported a previous PCOS diagnosis and 2 women were newly diagnosed), resulting in a prevalence of 26.7%.
CONCLUSIONS—We concluded that PCOS occurs frequently among premenopausal women with type 2 diabetes.
Footnotes
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Address correspondence and reprint requests to John E. Nestler, MD, Medical College of Virginia, P.O. Box 980111, Richmond, VA 23298-0111. E-mail: nestler{at}hsc.vcu.edu.
Received for publication 10 November 2000 and accepted in revised form 22 February 2001.
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