Diabetes and ST Elevation Myocardial Infarction

How successful is intravenous thrombolysis for the diabetic heart?

  1. Michael N. Zairis, MD,
  2. Stamatis S. Makrygiannis, MD,
  3. Olga A. Papadaki, MD,
  4. Anastassios G. Lyras, MD,
  5. John P. Kouzanidis, MD,
  6. Olga S. Ampartzidou, MD,
  7. Stelios M. Handanis, MD,
  8. Spyros M. Argyrakis, MD and
  9. Stefanos G. Foussas, MD, FESC, FACC
  1. 1From the Department of Cardiology, Tzanio Hospital, Piraeus, Greece

    Early resolution of ST-segment elevation is associated with enhanced clinical outcome following ST elevation myocardial infarction (STEMI). According to previous studies, the incidence of successful reperfusion following STEMI treated with thrombolytic regimen is similar for type 2 diabetic subjects and nondiabetic subjects as assessed by “snapshot” electrocardiographic or angiographic criteria (1). Nevertheless, type 2 diabetic subjects thrombolysed because of STEMI still seem to fare worse, manifesting impaired left ventricular function or long-term prognosis (2).

    The aim of this prospective study was to test the hypothesis that type 2 diabetic subjects may have a protracted …

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