White Blood Cell Count Is Positively Correlated With Albumin Excretion Rate in Subjects With Type 2 Diabetes
- Franco Cavalot, MD,
- Paola Massucco, MD,
- Paolo Perna, MD,
- Monica Traversa, MD,
- Giovanni Anfossi, MD and
- Mariella Trovati, MD
- From the Diabetes Unit, Department of Clinical and Biological Sciences of the University of Turin, San Luigi Gonzaga Hospital, Orbassano (Turin), Italy
White blood cell (WBC) count is one of the main inflammatory markers that predict cardiovascular events (1) and is a component (in nondiabetic subjects) of the insulin resistance syndrome (2), a clustering of cardiovascular risk factors showing insulin resistance as a common denominator (3). It is not known whether WBC count correlates with albumin excretion rate (AER), a component of the insulin resistance syndrome conferring a particularly strong risk of cardiovascular morbidity and mortality (3).
To evaluate whether WBC count correlates with AER in type 2 diabetes, we evaluated 659 Italian type 2 diabetic patients (354 men and 305 women) followed-up at the University Diabetes Unit of the San Luigi Gonzaga Hospital in Orbassano, Turin, Italy, who were not affected by neoplastic, inflammatory, infective, or liver diseases. AER was determined by nephelometric …
