Improvement of Asthma After Administration of Pioglitazone
- Yoshiaki Hashimoto, MD and
- Kazuhiko Nakahara, MD
- From the Department of Clinical Laboratory Medicine, Faculty of Medicine, the University of Tokyo, Tokyo, Japan
We describe the case of a 71-year-old man who was being followed as an outpatient for type 2 diabetes, hyperlipidemia, hypertension, and asthma. He was a past smoker with a BMI of 25.6 kg/m2. Because he had only mild wheezing at night, he was not under medical treatment for asthma. As his level of HbA1c remained between 6.6 and 6.8% under treatment with 2.5 mg glibenclamide, 30 mg pioglitazone (an insulin-sensitizing drug) was added to his treatment. Several days later, he noticed that his wheezing had disappeared. The pulmonary function tests showed improvement of forced vital capacity from 2.33 to 3.02 l and forced expiratory volume in …
