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Correlation of Serum Leptin Levels With Insulin Sensitivity in Patients With Chronic Hepatitis-C Infection

  1. Oral Öncül, MD1,
  2. Cýhan Top, MD2 and
  3. Þaban Çavuþlu, MD1
  1. 1Department of Infectious Disease, Gülhane Military Medical Academy, Haydarþa Training Hospital, Ýstanbul, Turkey
  2. 2Department of Internal Medicine, Gülhane Military Medical Academy, Haydarþa, Training Hospital, Ýstanbul, Turkey

    Diabetes is a less-recognized association of hepatitis-C virus (HCV) infection, although several recent studies provide data linking HCV infection and diabetes (1–5). To investigate whether patients with chronic HCV infection without evidence of cirrhosis have an increased risk of diabetes, we conducted a case-control study in 44 consecutive eligible patients with HCV infection and no clinical or histological evidence of cirrhosis and in 20 control subjects without liver disease who were matched by age, sex, and BMI. All 44 …

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