High Prevalence of Insulin Resistance and Metabolic Syndrome in Overweight/Obese Preadolescent Hong Kong Chinese Children Aged 9–12 Years
- Rita Y.T. Sung, MD, FRCP1,
- Peter C.Y. Tong, PHD, MRCP2,
- Chung-Wah Yu, MB, BS, MPhil1,
- Patrick W.C. Lau, PHD3,
- Geoffrey T.F. Mok, MB, BS, MRCP1,
- Man-Ching Yam, MB, BS, MRCP1,
- Peggo K.W. Lam, MPhil4 and
- Juliana C.N. Chan, MD, FRCP2
- 1Department of Pediatrics, the Chinese University of Hong Kong, the Prince of Wales Hospital, Shatin, Hong Kong
- 2Department of Medicine & Therapeutics, the Chinese University of Hong Kong, the Prince of Wales Hospital, Shatin, Hong Kong
- 3Department of Physical Education, Hong Kong Baptist University, Kowloon, Hong Kong
- 4Centre for Clinical Trials and Epidemiological Research, the Chinese University of Hong Kong, the Prince of Wales Hospita, Shatin, Hong Kong
During the past decade, the rising prevalence of childhood obesity has been accompanied by a rapid increase in young-onset type 2 diabetes (1). The associations among obesity, insulin resistance, hypertension, and dyslipidemia are not well defined in preadolescent children. Furthermore, the impact of family history of diabetes, low birth weight, and non–breast-feeding on the clustering of features of insulin resistance syndrome in children remained to be determined. In a cross-sectional study of 271 primary school children between 9 and 12 years of age, we compared the effects of family history of diabetes, breast-feeding, and extremes of birth weight on …
