ACE Insertion/Deletion Genotypes and Angiotensin II Receptor Blockade in Diabetic Nephropathy
Is there a light at the end of the tunnel?
- Steen Andersen, MD1,
- Peter Jacobsen, MD1 and
- Hans-Henrik Parving, MD, DMSC12
- 1Steno Diabetes Center, Gentofte, Denmark
- 2Faculty of Health Science, University of Aarhus, Aarhus, Denmark
- Address correspondence to Steen Andersen, Steno Diabetes Center, Niels Steensens Vej 2, DK-2820 Gentofte, Denmark. E-mail: stan{at}steno.dk
Pharmacogenetics is the study of genetic influence on response to drugs. This is an area of increasing attention due to the possibilities of improving overall treatment effects in patients through individual strategies. Mogensen (1) addresses this subject and diabetic renal disease in relation to our study. In the study in question (2), we masked and prospectively investigated the renoprotective effects of angiotensin II receptor blockade (ARB) in hypertensive type 1 diabetic patients with diabetic nephropathy homozygous for …
