Lowering the Criterion for Impaired Fasting Glucose Is in Order

  1. Saul Genuth, MD
  1. Address correspondence to Saul Genuth, MD, Case Western Reserve University, Division of Clinical and Molecular Endocrinology, 10900 Euclid Ave. Cleveland, OH 44106-4951. E-mail: smg15{at}cwru.edu


Editor’s comment: Because of the controversial nature of the new lowered criterion for IFG, I offered the Chairman of the Expert Committee an opportunity to respond to my commentary on the subject. I would only point out that Dr. Genuth’s reference 8 shows an association between glycemia and cardiovascular disease (as have many other reports), but to date, five prospective studies, analyzed either singly or as a metanalysis, have been unable to demonstrate a beneficial effect of lowering glycemia on cardiovascular disease outcomes.


  • A table elsewhere in this issue shows conventional and Système International (SI) units and conversion factors for many substances.

    • Accepted September 25, 2003.
    • Received September 25, 2003.
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