The Cutoff Value of Fasting Plasma Glucose to Differentiate Frequencies of Cardiovascular Risk Factors in a Korean Population
- Dong-Jun Kim, MD1,
- Kwang-Won Kim, MD, PHD2,
- Nam-Han Cho, MD, PHD3,
- Jung-Hyun Noh, MD, PHD1,
- Myung-Shik Lee, MD, PHD2 and
- Moon-Kyu Lee, MD, PHD2
- 1Department of Internal Medicine, Inje Unversity College of Medicine, Koyang, Korea
- 2Department of Medicine, Division of Endocrinology and Metabolism, Sungkyunkwan Unversity School of Medicine, Seoul, Korea
- 3Department of Preventive Medicine, Ajou University School of Medicine, Suwon, Korea
- Address correspondence to Prof. Kwang-Wom Kim, Sungkyunkwan University School of Medicine, Department of Medicine, Division of Endocrinology & Metabolism, Samsung Medical Center, 50 Ilwon-dong, Kangnam-ku, Seoul 135-710, Korea. E-mail: kwwkim{at}smc.samsung.co.kr
Diabetes and impaired glucose tolerance (IGT) are associated with increased cardiovascular mortality. Almost all studies, however, failed to detect evidence of the presence of a fasting plasma glucose (FPG) threshold for risk of cardiovascular disease that would clearly identify groups with a low or high risk (1,2). Some studies suggested that an FPG of 5.4–5.7 mmol/l has been found to be closer to a 2-h cutoff of 7.8 mmol/l both in terms of the sensitivity for future diabetes and in defining a category of similar prevalence to IGT (3,4). The interrelationships between cardiovascular risk factors and glucose levels may vary between different populations. Therefore, these findings need to be tested in other populations with different …
