Safety Issues on Metformin Use
- Saleh A. Aldasouqi, MD1 and
- Daniel S. Duick, MD2
- 1King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia
- 2Endocrinology Associates, Phoenix, Arizona
- Address correspondence to Saleh A. Aldasouqi, MD, King Fahd Miltary Teaching Hospital, P.O. Box 9862, Jeddah 21159, Saudi Arabia. E-mail: saldasouqi{at}pol.net
We read with interest the letter by Faichney and Tate (1) in the May issue of Diabetes Care. We would like to comment on metformin and the risk of lactic acidosis; however, we do not have data to refute the hypothetical relevance of diabetic ketoacidosis to the risk of lactic acidosis (1). We believe that the aforementioned letter and relevant reports (2–4) may negatively affect the future use of metformin, not only in type 1 (1) but also in type 2 diabetic patients. In this regard, the report by Horlen et al. (2), which addressed physicians’ lack of adherence to …
