Prevalence of Type 1 Diabetes-Related Autoantibodies in Adults With Celiac Disease
- Graziella Bruno, MD,
- Silvia Pinach, MD,
- Silvia Martini, MD,
- Maurizio Cassader, MD,
- Gianfranco Pagano, MD and
- Carla Sategna Guidetti, MD
- From the Department of Internal Medicine, University of Torino, Torino, Italy
Studies have shown a 4% prevalence of celiac disease in type 1 diabetic patients. Few data, however, are available on the prevalence of type 1 diabetes-related antibodies in patients with celiac disease, with studies being limited by the recruitment of low numbers of children only (1,2). We have assessed prevalence of type 1 diabetes-related autoantibodies (islet cell antibody [ICA], GAD antibody [GADA], and antibodies to the protein tyrosine phosphatase-related IA-2 [anti-IA2]) in a cohort of 378 nondiabetic adults with celiac disease (89 untreated and 289 treated with a gluten-free diet), aged 33.9 …
