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Is the Fat Still in the Fire?

Response to Greenfield et al.

  1. Burton E. Sobel, MD
  1. From the Department of Medicine, University of Vermont College of Medicine, Burlington, Vermont
  1. Address correspondence to Burton E. Sobel, MD, Department of Medicine, University of Vermont, Colchester Research Facility, 208 South Park Dr., Colchester, VT 05446. E-mail: burt.sobel{at}vtmednet.org

The comments of Greenfield et al. (1) in this issue of Diabetes Care regarding the recent editorial entitled “Coronary Disease in Type 1 Diabetes: Causal Contiguity and Clinical Implications” (2) are most appreciated. What was stated in the editorial regarding insulin resistance in type 1 diabetes is found in the following paragraph: “On purely statistical grounds, one would anticipate insulin resistance in many people with type 1 diabetes. In addition, however, intensive treatment of type 1 diabetes appears to increase central obesity. In fact, it has been noted that ‘insulin treatment …

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